Retreats at Longlea Conference Center are traditional, silent retreats, conducted by priests of the Prelature of Opus Dei for either men or women. The conference center, located on 843 acres next to the Blue Hills of Virginia, includes a chapel, a dining room, living rooms, class rooms, and 29 bedrooms which can accommodate up to 35 individuals if shared rooms are used. Walking trails and a small shrine dedicated to the Blessed Virgin help those attending the retreat to maintain a spirit of prayer and recollection.

Each day of the retreat includes Holy Mass, four or five meditations given by the priest, Exposition and Benediction of the Blessed Sacrament and recitation of the rosary. The priest conducting the retreat is available for the Sacrament of Reconciliation as well as for personal consultation.

All meals are provided in family style. Only certain medical diets can be accommodated; diets need to be cleared with the staff prior to the retreat to confirm they can be prepared.